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  ű ǰ   2017-07-27 5:31:52

					

					
 

HL 17-25 

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ű ǰ Ʒ ˷帮 ῡ Ͻñ ٶϴ.

117. ŽŰ

Aripiprazole
IAP3 300mg(Aripiprazole monohydrate 312mg)/1.5ml SR Abilify Maintena(ī) (117)
IAP4 400mg(Aripiprazole monohydrate 416mg)/2ml SR Abilify Maintena(ī) (117)

[] Dopamine(D2) 5-HT1A ü κ ȿ ۿϰ 5-HT2A ü ۿϴ Ź ֻ.
[ȿ] źп() ġ.
[] 汸 Ƹ ༺ Ȯ , Ŵ 400mg ﰢ Ǵ кαٿ IM( 26 ̻), ù 汸 Ƹ(10~20mg) 14ϰ , ٸ 汸 ź࿡ ȭ ȯڴ ϰ ִ ź๰ 14ϰ . 400mg ̻ ִ 300mg . ģ : ° Ǵ ° Ϸκ 5 ̻ Բ 汸 Ƹ 14ϰ , ° ̻ Ϸκ 6 ̻ Բ 汸 Ƹ 14ϰ . CYP2D6 , 14 ̻ CYP2D6 CYP3A4 300mg , 300mg ϴ ȯڴ .
[] ü, ºҴ, ֻ , , , , , , , , ü߰, , , , .
[ݱ] ࿡ ȯ.
[] , , , ü , ϰ, μ , , ADHD, νķ°  ȭ ڻ浿 ɼ ִ ȯ, Ӻ, . ġŸ ȯ ȯڿ ȿ Ȯ. ̻, , ϰ , . Ű̿ Ǽ ı, ̻, , ̻, ü, , ȣ߱, . ֻ 빰 ֻϰ ֻ . ݴ ﰢ Ǵ кαٿ ֻ.
[Ӻ] FDA C, Ӻαݱ 2.
 

149. Ÿ ˷

Allergovit
IALEGA ʱ Set(Allergen extract Vial A(3,000TU/3ml) + Vial B(30,000TU/3ml))(˷ͳ) (149) ޿
IALEGB Set(Allergen extract Vial B(30,000TU/3ml) 2)(˷ͳ) (149) ޿

[] ˷ ݺ Ͽ Ư ˷ ӻ, .
[ȿ] IgE Ű allergen ˷⼺ , ḷ ġ.
[] ȯ κ ΰ 뷮 , Ȳġ 5~6ġ ű õõ ֻ. 5 , ּ 30 ̻ ͸ . ÿ : ɰ 7 1 뷮 󵵺 Ͽ ִ 뷮 (ȹ - ̾ A 0.1ml, 0.2ml, 0.4ml, 0.8ml, ̾ B 0.15ml, 0.3ml, 0.6ml(ִ뷮)). : ġᰡ 1 ӵǴ , ִ 뷮 520% ȭ 2 , ȭⰡ ִ 뷮 ؿ ٽ 2 2 뷮 ϸ, 48ַ ø . Ϲ ġⰣ 3, ϸ ȭ 1 ġ .
[] , , , ֻ (, ȫ, ), , , ä, ε巯, , , ȣ, .
[ݱ] ࿡ ι ȯ, ߵ~ õ, , Ȯ, / ȯ, ޼ Ǵ ȯ, ɺ, 鿪 ȯ, ȯ, ȯ.
[] ACE ȯ, ȯ . ޼ ȯ (õ, ˷⼺ , , ) . ּ 1 ΰ, 2 ϸ, 7~14 . 5 ̸ Ҿƿ ȿ Ȯ. 12 ̳ . (28).
[Ӻ] Ȯ.
[] ȯڿ ׿ , , պ ٸ, ȯں ó 6~8 ̻ Ⱓ ҿ. 

421. ׾Ǽ

Pertuzumab
IPTMAB 440mg/14ml Vial Perjeta(ν) (421)

[] HER2 ܹ dimerization domain Ͽ üȭ(dimerization) ν HER2 ϼ İ õ ȣ (MAPK, PI3K ) ϰ ü (ADCC) Ű.
[ȿ] -HER2 ġ Ǵ ȭп ġḦ HER2 缺 ȯڷμ ̼ Ǵ Ұ ߼ ȯڿ Ź ƾ . , Ǵ ʱ ܰ( 2 ʰ) HER2 缺 ȯ μ ÷ο, ǷŰ Ŭĸ̵(FEC) Ǵ īöƾ ϴ ġ ȯ ƾ Ź .
[] 2Vial(840mg) NS 250ml (3mg/ml)Ͽ 60а IV. 3ָ 1Vial(420mg) NS 250ml (1.6mg/ml)Ͽ 30~60 IV. ƾ ʱ 8mg/kg, 3ָ 6mg/kg, Ź ʱ 75mg/m2, 3ָ 100mg/m2 . ģ : Ϸκ 6 ̻ , ٽ ȸ뷮 2Vial 60а IV, 3ָ 1Vial 30~60а IV.
[] , Ż, ȣ߱, , , , εο, ½ɽDZɺ, ι, ʽŰ溴, , , , Ƿ, , , ȣ, , .
[ݱ] ࿡ ι ˷ ȯ.
[] ½ɽ ɺ ƾ  3ְ . ԰ù ߻ ӵ ̰ų ޾ؾ ϸ 氨Ǹ 簳 . Թ ߴ. ġ ù 3ֱ ߿ ȣ߱, , . ȭҹ, non-PVC ÷ɹ鿡 0.9% Ŀ ֻ 2~8 24ð . Ʈν(5%) ׿ . (2~8).
[Ӻ] FDA D, Ӻαݱ 2.

  

613. ַ ׻꼺տ ۿϴ

Tubes
BTB 1 Isoniazid 75mg, Pyrazinamide 400mg, Rifampicin 150mg, Ethambutol HCl 275mg(񾾿) (613)

[] Isoniazid - mycolic acid ռ Ͽ ı. Pyrazinamide - macrophages ϴ ִ ٱ . Rifampicin - DNA RNA polymerase b-subunit Ͽ RNA ռ . Ethambutol - Mycobacteria Ͽ RNA ռ .
[ȿ] 8 ̻ Ҿ ġ.
[] 1 1ȸ 1ð . 30~37kg - 2, 38~54kg - 3, 55~70kg 4, 71kg ̻ 5(ü 30kg ȯڿ ).
[] Ƿ, , , ȥ, , ȱ, Ŀ, , , θ, ̻, , , Ҿ, ü׺, , ʽŰ濰, , , Ӿ, , , , dz, Ƴʶ .
[ݱ] ȯ, ޼ շ, , Ǹ, , ޼ dz ȯ, ̼ҴϾ Ƽƿȭ ӵ ̻ ι ȯ, ڳ, ׾ , ҷź , Ӻ.
[] ȯ, , , ڿ , ڿ , , , ȯ. պ Ǿ Ƿ ش 뷮 ʿ óؾ . Ű ۿ, ð , , ι ߻ . , , Ÿ, , Ʈ Ʈ Ӱ .
[Ӻ] FDA C.

  

622. װ

Bedaquiline
BBEDA 100mg(Bedaquiline fumarate 120.89mg)/Tab Sirturo() (622)

[] Diarylquinoline ׸ڹ׸ M. tuberculosis ʿ ATP ȿҺü ȸ ܹ .
[ȿ] 18 ̻ (ȯڷκ и ̼ҴϾ ǽſ ü ) .
[] 1~2 : 1 1ȸ 400mg, İ Բ . 3~24 : Ͽ 3ȸ, 200mg İ Բ ( ּ 48ð ̻), ȯڷκ и ְ ü 3 ̻ ๰ . ġ 3 : żϰ ϰ ִ 3ȸ 簳(ּ 24ð , ִ 600mg/Week).
[] , , , , , QT, , , ƹ̳ȿ .
[ݱ] ҳ ȯ.
[] ٱ ẹ ġ, ġ, ġ ټ ׻(NTM) ġῡ ȿ Ȯ. QT, CYP3A4 , CYP3A4 .
[Ӻ] FDA B.
[] [ݱ] BDOM, PDOM - QT  

Tubes 2
BTB2 1 Isoniazid 150mg, Rifampicin 300mg(񾾿) (622)

[] Isoniazid - mycolic acid ռ Ͽ ı. Rifampicin - DNA RNA polymerase b-subunit Ͽ RNA ռ .
[ȿ] (ʱ̳ δ ).
[] 1 1ȸ 2, 1ð Ȥ 2ð . , Ű溴 ȯ(索 ȯ ) û ȯڴ Ǹ .
[] , , 󺹺, , ʽŰ濰, Ŀ尨, Ȳ, θ, , ǰ, , ߿, , Ƿ, , , ȴٸ , , BUN , , , ε巯, , , ȣ걸 , , , , , , , ö𱸼 , ҷ , , .
[ݱ] , ι, ȯ, /.
[] , , , , ִ ȯ, , ߵ ȯ, Ȳ5ȣ(¿ο FCF) ˷ ȯ. , , Ÿ, , ƮƮ Ӱ . 15 Ҿ ȯڿ ȿ Ȯ.
[Ӻ] FDA C.

  

631. ŷ

Pentaxim
JJPEN 1Pk(1Vial(Hib)+1PFS(DTaP+IPV 0.5ml))(Ľ) (631) ޿

[ȿ] ׸ Ļdz, , (ҾƸ) ʷ罺 ÷翣 տ ħ .
[] 1ȸ 0.5ml, 2, 4, 6 3ȸ . ʵø Ź и ̾˿ ־ 籸 IM.
IM.
[] ֻ ҹ(ȫ, ߿, , , ), , ڱذμ, ߿, Ŀ尨, , , Ҹ, , .
[ݱ] , , ۷Ÿ˵, ׿̽, Ʈ丶̽, ͽB ˷ , , ߿, ޼ȯ, 7 ̳ .
[] 鿪 ġḦ ޴ ȯ, , Ļdz ̵ -ٷ ı , ȯ, շ. ̼ 48~72ð ȣ ͸. 8 ̸ Ҿƿ ȿ Ȯ. MMR Ǵ B Ű ٸ . (2~8).
[Ӻ] FDA C.
[] ʼ, [󼼼] 1Vail Haemophilus influenza type B polysacharide conjugated with tetanus toxoid[ : Haemophilus influenzae type b 1482(ֹȣ 2164), մܹ : Clostridium tetani Havard 49205(ֹȣ 1472C)] 10(и), 1PFS(0.5ml) Diphtheria toxoid(ָ : 1514-N-3S) 30IU, tetanus toxoid(ָ : 1472-C) 40IU, B. pertussis toxoid(ָ : 1591) 25, filamentous hemagglutinin (ָ : 1591) 25, inactivated polio virus types 1(̷ָ : Mahoney) 40з ʴ Է, inactivated polio virus types 2 (̷ָ : MEF-1) 8з ʴ Է, inactivated polio virus types 3(̷ָ: Saukett) 32з ʴ Է.

  

2017. 07. 27.

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